Partnering Opportunities

HKPB Scientific is currently seeking strategic co-development partnerships with leaders in the medical device arena. Co-development projects may begin with a feasibility agreement to develop a customer-specific solution leading to development and licensing agreements. HKPB Scientific is a results driven company and our business is delivering on milestones and goals within a project framework.

How can Partners benefit from the TM – CMC technology?

HKPB Scientific has developed TM – CMC to meet the growing demand for innovative biomedical device coating solutions and to service a number of unmet needs in that large and growing market. This groundbreaking innovation can be tailored to meet specific customer’s needs delivering the following benefits:

Clinical Benefit

HKPB believes that TM – CMC can offer the following clinical benefits.

Therapeutic Agents

  • The cooling properties of the liquid portion of the aerosol uniquely allows for the incorporation of thermally sensitive, therapeutic agents into a coating in a single step process.
  • Loading of therapeutic agents can be controlled by precise control of process parameters.
  • A homogeneous distribution of therapeutic agent within the coating can be achieved due to the inherent characteristics of the TM – CMC process.

Biocompatibility

  • No complex chemicals, curing agents or polymerisation initiators are needed to adhere TM-CMC coatings to medical devices.
  • No subsequent heat treatments, which may result in the degradation of the coating materials, are needed for coating formation.
  • Water, which is inherently biocompatible may be used in TM – CMC.

Device Integrity

  • TM – CMC prevents heat damage at the surface of medical devices that can occur with high temperature coating methodologies.

Cost and Process Benefits

HKPB believes that TM – CMC can offer the following cost and process benefits.

Single Step Process

  • In contrast to other multi-step coating processes TM – CMC allows the formation of drug eluting coating instantaneously without the requirement for pre or post processing.
  • Significantly reduces manufacturing costs in terms of time, labour and capital equipment.
  • Reduced potential for unwanted contamination of devices.

Manufacturability

  • TM – CMC combines the equipment platforms from techniques that have long been used in the surface modification arena: atomisers and shot peeners.
  • The automation, Computer Numerical Control (CNC) etc. required to implement TM – CMC has already been developed and integrated into manufacturing line.
  • Automation and precision means that with TM – CMC quality and reproducibility are standard with minimum waste of expensive therapeutic agents.

Flexibility

  • TM – CMC may be used to coat a broad range of devices made of metal, ceramic or hard polymers.
  • A vast spectrum of coating materials including polymers, ceramics, metals and thermally sensitive agents can be coated onto medical devices in a single step.
  • The coating composition is readily controlled through the precursor composition.
  • A wide range of precursor compositions can be used including individually or in combination solutions, suspensions, colloidal suspensions, gels, sols or resins.